June Robinson. AC may be painless, but it can lead to Clinical Information and Differential Diagnosis of Cheilitis, Actinic References. The pathological features of actinic cheilitis are variable thickening or atrophy of the lip, partial thickness epidermal dysplasia , … A skin biopsy may be taken if skin cancer or an inflammatory cause of cheilitis is suspected. It is significantly more common in men, elderly patients, and fair-skinned patients. It usually appears as very chapped lips, then may turn white or scaly. The differential diagnosis of exfoliative cheilitis include: • Atopy • Candida yeast infection • Hypervitaminosis A • Actinic cheilitis • Cheilitisglandularis • Contact dermatitis • Photosensitivity. David Picascia. Saunders. Journal of the American Academy of Dermatology, 1987. 2 Cheilitis granulomatosa: A rare condition manifesting as an episodic, non-tender enlargement of one or both the lips. The condition is also known as solar keratosis.. Actinic keratoses are ultraviolet (UV) light-induced lesions of the skin, which are by far the most common lesions with malignant potential to arise on the skin. Chronic actinic cheilitis with leukoplakia actinic cheilitis 21. The differential diagnosis of AC includes actinic lichen planus (ALP), herpes simplex lesions, exfoliative cheilitis, contact cheilitis (CC), autoimmune blistering disease including pemphigus vulgaris (PV), lichenoid drug eruptions, cheilitis granulomatosa (CGM), cheilitis grandularis (CGL), and early carcinoma in situ (CIS) [11, 12]. Skin biopsy is the golden standard regarding the evaluation of a persistent suspicious lesion on the lip. Differential diagnosis. The term actinic keratosis (AK) was coined in 1958 and means literally thickened scaly growth (keratosis) caused by sunlight (actinic). Generally, the forms most commonly reported in the literature are angular, contact (allergic and irritant), actinic, glandular, granulomatous, exfoliative and plasma cell cheilitis. Actinic cheilitis - the same lesion on the lip. Typically, they occur in middle-aged or older men with light-coloured skin and a history of chronic sun exposure. Search. Essentially it is a burn, and a variant of actinic keratosis which occurs on the lip. Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). (2009). Eczematous cheilitis: Reddish scaly eruptions are present in both lips and perioral skin with edema, fissures, vesicles and superficial ulceration [3]. Factitious cheilitis is a chronic condition characterized by crusting and ulceration that is probably secondary to chewing and sucking of the lips. Actinic cheilitis is a lesion of the lip that is analogous to actinic keratosis. What is the dermoscopic differential diagnosis of actinic keratosis? Cheilitis can also be a symptom of a contact reaction to an irritant or allergen, or may be provoked by sun exposure (actinic cheilitis) or drug intake, especially retinoids. Download Full PDF Package . Actinic cheilitis is the counterpart of actinic keratosis of the skin and can also develop into squamous cell carcinoma. 44. Although cheilitis as a term describing lip inflammation has been identified and recognized for a long time, until now there have been no clear recommendations for its work-up and classification. It is essential to distinguish between cheilitis (benign inflammation), premalignant actinic cheilitis, and squamous cell carcinoma. Create a free account to download. It may coexist with solar lentigo, cutaneous squamous cell carcinoma, and lentigo maligna. Lumican as a novel marker for differential diagnosis of Bowen disease and actinic keratosis. Freedberg, Irwin M., ed. Like discrete actinic keratoses, actinic cheilitis is also a premalignant condition related to cumulative lifetime sun exposure. Differential diagnosis can include chronic lip licking, granulomatous cheilitis, drug-induced cheilitis, contact dermatitis, cheilitis glandularis, lupus erythematosus, and lichen planus. New York: Mosby, 2003. ... • Lymphoma is a rare differential diagnosis. Actinic Cheilitis . Differential diagnosis: The clinician should consider squamous cell carcinoma as the primary diagnosis. 2004 Edition | Editors: N. Levine, C. C. Levine. It is a pre-cancerous condition squamous cell carcinoma of the lip) that most commonly occurs in light-skinned individuals, and in people who live in hot, dry climates and/or work outdoors, like construction workers. Actinic cheilitis is a diagnosis made from clinical and histopathology evaluation. Differential Diagnosis of Actinic Keratosis The relatively nonspecific clinical features of AK can make differential diagnosis challenging. “Actinic cheilitis:a review of the etiology, differential diagnosis, and treatment”. It is a premalignant condition, as it can develop into squamous cell carcinoma (a type of mouth cancer The patient may complain of prurigo, burning sensation and tenderness of affected area and eczema in other parts of the body, depending on the source and manifestation of allergy aiding differential diagnosis. Chicago, IL With today's increase in sun worshippers, the number of sun-induced skin lesions is increasing. Actinic cheilitis is a diagnosis made from clinical and histopathology evaluation. 255-64. Actinie cheilitis: A review of the etiology, differential diagnosis, and treatment. Download with Google Download with Facebook. Medicines and therapies. David Picascia. 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